Treatment method

Glue vein treatment

More about Glue vein treatment

Treatment with bioglue entails injecting into the varicose lumen vein a special biological glue — cyanoacrylate, which is similar to the adhesives that have been used for many years in other spheres of medicine. It causes instant conglutination of the vein which is the root cause of the disease and the source of filling of varicose tributaries (which create the unsightly web of veins on legs). By treating the source of the disease this technique provides a gradual reduction of varicose tributaries due to the lose of their blood source. Furthermore symptoms of the varicose disease are also eliminated: heaviness in legs, swelling, crumps.

The prevalence of a low injury rate and no need for anesthesia makes it possible to treat patients with advanced form of the disease and those with complications — varicose eczema, trophic ulcers, and thrombophlebitis.

Glue treatment is an innovative method of treatment for varicose veins and is revolutionizing the field of phlebology. For patients who select this treatment, benefits include no need for anesthesia or compression stockings, while patients can return to their normal activities immediately following the procedure including sunbathing, should they be going on vacation.

Advantages of glue treatment of varicose

  • Numerous international clinical trials have demonstrated the safety and efficiency of this treatment method.
  • As the procedure does not require the use of local tumescent anesthesia it frees the patient from discomfort related to numerous injections which are required for treatment via endovenouse laser ablation or radiofrequency ablation.
  • Patients are no longer required to wear compression garments during the post surgery period.
  • It is not a thermal procedure (use of high temperature), which excludes the possibility of any related complications (burns, nerve injuries).
  • The treatment takes approximately 20 minutes making it possible for the patient to return to work on the day of the procedure, and does not require taking any medications either before or after the procedure.
  • It is perfectly suited for treatment during the summer period, since it does not require wearing compression stockings, and makes it possible for the patient to expose their legs to sunshine.
Additional information for patients
How glue works

Bioglue belongs to the class of medical glues — cyanoacrylates. It glues the vein walls together immediately after injection. As soon as the glue conglutinates the problematic vein, the latter hardens (is sclerosed) and over time resolves the issue. The blood flow is redistributed to healthy veins.

What is the bioglue made of?

Bioglue belongs to a class of medical "superglues" known as cyanoacrylate. It is scientifically formulated and differs in some special characteristics from other medical glues:

  • When contacting blood within a venous wall it is polymerized immediately. Meaning that it instantly glues the vein when injected, with minimum migration;

  • It also possesses antimicrobial characteristics.

Where else is cyanoacrylate used for?

  • Orthopedics

  • Ophthalmology

  • Stomatology

  • Cosmetic procedures

  • To close vessels in the case of arteriovenous malformation, varikocele, pelvic congestion syndrome and varicosity of gullet and stomach.

Bioglue efficiency is well-proven

  • Research evidences treatment efficiency as high as 92-98% which corresponds to similar results of treatment by means of EVLA or RF ablation.

  • This method of treatment has been used for the last five years in the USA and Europe. Research of the method has demonstrated excellent results in the early and medium follow-up.

When and for whom bioglue treatment is prescribed

  • Phlebologist’s consultation is arranged, including clinical examination and detailed ultrasonic duplex scanning of veins. It shows the condition of both superficial and deep venous system. It is determined which veins exactly are affected – and this determines the viability of using the glue treatment method.

  • Treatment plan choice is strictly individual. It considers both the affected veins anatomy data and the patient's wishes concerning the treatment period and results.

  • Depending on this, the need for possible additional sclerotherapy or miniphlebectomy treatment can be considered and discussed.

How to prepare for the procedure with bioglue

  • No special premedication is needed.

  • Before treatment the patient’s legs must be shaved.

  • A basic panel of blood tests needs to be performed.

  • It is recommended to put on comfortable footwear because after the procedure a short walk is needed.

How is a patient treated with bioglue?

  • Detailed ultrasonic pre-surgery examination of the affected vein with marking is conducted. Optimal access to the varicose vein is determined – it is the place of puncture (piercing) of the vein through which the systems of glue delivery are introduced.

  • During the procedure, the place of access to the vein is anesthetized by means of injection via a small needle which can causes minimal discomfort to the patient.

  • The system of glue delivery is a thin flexible catheter.

  • After anesthetizing the point of access to the vein, the doctor inserts a catheter into the patient’s leg. This stage of treatment is not sensed by the patient.

  • The catheter is positioned in the varicose vein as exactly defined by the scanning guidance of an ultrasonic sensor. Following which a small amount of glue is gradually injected.

  • During this procedure the patient may feel a slight discomfort. The procedure is directed with ultrasonography and lasts only several minutes.

  • After the glue injection, the catheter is removed and a small bandage is applied for several hours.

What to do after the procedure with glue treatment

  • Patients are provided with individual recommendations based on their lifestyle during the post-surgery period.

  • After the treatment, walking for 20-30 minutes is recommended. Patients can drive home or use public transport.

  • Patients are provided with the doctor’s direct phone number in case any questions arise.

  • Patients can return to their habitual lifestyle, except for recommendations to avoid long-time standing and big static loads within 48 hours.

  • If a patient has to go on an air trip which will last over four hours within three to four weeks after the procedure, the patient may obtain additional recommendations (to take low-molecular heparins before the flight, or use compression garments and to walk or to stretch legs every hour during the flight).

  • Ultrasonic examination is carried out in the second week and 6 months after the procedure.

Some side effects of the procedure

  • According to the research data, these are extremely rare.

  • Slight pain or discomfort along the length of the treated vein within 1-2 weeks. It is treated by means of taking anti-inflammatory drugs.

  • Phlebitis or inflammation (most often in the lower part of the hip). It is treated by means of taking antiinflammatory drugs and wearing compression garments.

  • Paresthesias (skin numbness) — it is described in rare instances; it is temporary and results from inflammation process; it disappears after the patient is treated with anti-inflammatory medicines.

Possible complications

Assuming the responsibility for treatment, our moral imperative is to inform patients about possible complications which are however extremely rare:

  • According to international research, the emergence of deep vein thrombosis or pulmonary embolism is — extremely rare but possible.